Although, there are some findings that Phf24-null rats exhibited increased sensitivity to chemically induced seizures, emotional hyper-reactivity, and cognitive deficits indicating that PHF24 is crucial for proper central nervous system function, particularly in preventing epileptogenesis and regulating emotional and cognitive behaviors (Serikawa et al. 2019), no correlation between stroke and PHF24 protein was observed in literature. Here, PHF24 is linked to Cognitive impairment.