Most research on ANGPTL3 has focused on conditions like type 2 diabetes and coronary artery disease.(35,36) It has been reported that ANGPTL3, 4, and 8 are elevated in obesity and type 2 diabetes(36) and that pharmacological inhibition of ANGPTL3 can reduce atherosclerotic lesion size.(35) Cinkajzlová et al.(37) found BMI to be an independent predictor of ANGPTL3 levels. This evidence concerns the gene ANGPTL3 and coronary artery disorder.