When dividing both the PCOS and control groups into six BMI-based subgroups normal weight (20-24.9 kg/m2), slightly overweight (25-29.9 kg/m2), and obese (30-39.9 kg/m2) there were significant differences in levels of ANGPTL3 and 8, omentin-1, leptin, IL-6, and TNF-α (p<0.05). The gene discussed is LEP; the disease is polycystic ovary syndrome.