TNF and polycystic ovary syndrome: The model, which included CRP, LDL, ANGPTL3, 4, 8, omentin-1, leptin, IL-6, TNF-α, and BMI, was found to be significant in identifying patients at risk of developing PCOS (Nagelkerke R2: 0.698, omnibus tests of model coefficients <0.0001, PPV: 80%, NPV: 90%) (Table 7).