Although the allergen panel was limited to only 2 dust mites, forgoing other allergens such as cockroach, cat fur, dog fur, molds, grass pollens, or Acacia, this was sufficient for the identification of atopy since allergy in the tropical urban environment of Malaysia and Singapore have been found to be primarily driven by mono-specific IgE sensitization against house dust mites [45]. This evidence concerns the gene IGHE and Allergy.