In the ventral horn region of lumbar spinal cord tissue from C9orf72-ALS Caucasian patients, Farg et al. (2017) reported that approximately 80% of vCHAT positive MNs from C9orf72 patients expressed p-ATM (Ser1981), compared to about 40% in controls (p < 0.05). The gene discussed is ATM; the disease is amyotrophic lateral sclerosis.