Next, three Cox regression models were conducted to adjust for potential confounders: Model 1: unadjusted; Model 2: adjusted for age, sex and race; Model 3 (AKI): adjusted for age, sex, race, BMI, ALT, glucose, creatinine and furosemide; Model 3 (Stage III AKI): adjusted for age, sex, race, BMI, creatinine, AST, bilirubin, hemoglobin, anion gap, hematocrit, albumin, lymphocytes, RRT, septic shock and SOFA score. This evidence concerns the gene ALB and acute kidney injury.