VCL and familial dilated cardiomyopathy: In genes related to DCM, the most frequent AAs were serine (e.g., SCN5A, MYH7), alanine (e.g., SCN5A, TNNT2), tyrosine (e.g., DSP, VCL), arginine (e.g., SCN5A, MYH7), and cysteine (e.g., MYH7, VCL).