In genes related to DCM, the most frequent AAs were serine (e.g., SCN5A, MYH7), alanine (e.g., SCN5A, TNNT2), tyrosine (e.g., DSP, VCL), arginine (e.g., SCN5A, MYH7), and cysteine (e.g., MYH7, VCL). This evidence concerns the gene MYH7 and familial dilated cardiomyopathy.