And compared with BMSCs-CM and ADSCs-CM, SHEDs-CM had higher levels of hepatocyte growth factor (HGF) expression, which plays an important role in SHEDs-CM treatment of myocardial infarction after ischemia-reperfusion, especially in terms of improvement of infarct size and inhibition of cardiomyocyte apoptosis (Yamaguchi et al., 2015). This evidence concerns the gene HGF and myocardial infarction.