We observed similar results upon celltreatment with AgnoTACs 2d, 7b* and 10d degrading the PLOD2 lysyl hydroxylase (Figure d–f), Parkinson’s disease associated transcriptionfactor CHCHD2 (Figure g–i), and the chromatin reader proteinBRD2 (Figure j–l) respectively. The gene discussed is PLOD2; the disease is glycogen storage disease VI.