To cite a study in relation to the non-genomic activity of AR, Benten et al (1997) studied that unconventional activation of calcium influx in T cells is the cause of plasma membrane receptors that are indirectly affected by testosterone-activating ARs.14 Most of the non-genomic studies todate have concentrated on abnormal AR stimulation, leading to cancer.15 Future clinical studies may well investigate androgen therapy as a promising avenue of treatment for demyelinating diseases and the aging process in both male and female patients. The gene discussed is AR; the disease is cancer.