In particular, TCLN results showed that serum miR−141, miR−375, and Let-7c, as well as urine miR−141, miR−375, PCA3 lncRNA, and T1-E2 mRNA, achieved AUC values above 0.7 in differentiating PCa patients from BPH patients and healthy controls, demonstrating their strong diagnostic potential. Here, PCA3 is linked to benign prostatic hyperplasia.