Four RNA biomarkers in urine EVs had AUC values of over 0.7, including miR−141 (PCa vs. HC: AUC = 0.785; PCa vs. BPH: AUC = 0.724), miR−375 (PCa vs. HC: AUC = 0.720; PCa vs. BPH: AUC = 0.714), PCA3 lncRNA (PCa vs. HC: AUC = 0.711; PCa vs. BPH: AUC = 0.761), and T1-E2 mRNA (PCa vs. HC: AUC = 0.822; PCa vs. BPH: AUC = 0.811) (Figure 3D). Here, PCA3 is linked to benign prostatic hyperplasia.