RET and glioma: Except for a tendency towards a more pronounced NPC-like tumor compartment, we did not observe any major deviation regarding the “Neftel” cell states in tumors from Pdgfbret/ret as compared to Pdgfbret/+ mice (Fig. S4B, C), reflecting the resilience of the dominant OPC/NPC state in this mouse model, and indicating that the phenotypical aberrance that we observed in glioma development upon pericyte removal was due to alterations in non-cell autonomous aspects of glioma biology.