Furthermore, comparing to GES-1 cells, expressions of TPP1 were notably enhanced in GC cell lines (MKN-45, HGC-27, BGC-823, MGC-803, and SNU-1 cells), among which highest expressions of TPP1 were observed in MKN-45 and HGC-27 cells (Fig. 1D). This evidence concerns the gene TPP1 and gastric cancer.