Our study demonstrated that MAOB-induced DNA damage also enhanced p53 K382 acetylation and upregulated PBRM1 (Fig. S12) in ccRCC cells, suggesting that PBRM1 recognition of this PTM may serve as another mechanism contributing to MAOB-mediated p53 reactivation. This evidence concerns the gene TP53 and nonpapillary renal cell carcinoma.