To next examine the in vivo effects of MAOB on ccRCC progression, we established a ccRCC-bearing mouse model by subcutaneously injecting luciferase (luc)-expressing Caki-1 cells (Caki-1/Neo-luc and Caki-1/MAOB-luc) into NOD-SCID mice. This evidence concerns the gene MAOB and nonpapillary renal cell carcinoma.