While elevated interferon signalling may also suggest automimicry in this cohort of GWI, the downregulation of IGHG1 and IGHV4–59 suggests reduced humoral immune responses and impaired antibody production, not reminiscent of the presence of autoimmunity which is inconsistent in GWI research [33,34]. The gene discussed is IGHG1; the disease is Autoimmunity.