SMAD3 and cancer: RBM47 is repressed by several EMT-related transcription factors, such as snail family transcriptional repressor 1 (SNAIL), snail family transcriptional repressor 2 (SLUG), signal transducer and activator of transcription 3 (STAT3), and SMAD family member 3 (SMAD3) in cancer cells [4, 5].