The lack of B-1a (Fig. 5K, L, 7H and I) and B-1b (Fig. 5M, N, 7J and K) B cells expansion in the spleen and peritoneal cavity during MHV68 infection could be due to the lack of NF-kB activity downstream of IL-17RA signaling in those cells. This evidence concerns the gene IL17RA and infection.