Given the overall reduction in splenomegaly (Fig. 3A), total B cells (Fig. 3B and C), and the germinal center response (Fig. 3D through I) in the spleen, along with no appreciable difference in the antibody response in MHV68-infected CD19 Cre-positive mice compared to CD19 Cre-negative mice (Fig. 4), the impact of B cell-intrinsic IL-17RA signaling on B-cell populations during MHV68 infection was determined at 16 days post-infection. Here, IL17RA is linked to infection.