APOL1 and diabetes mellitus: On univariate analysis, baseline variables associated with a more rapid annual eGFR decline included older age, diabetes mellitus, the use of RAAS inhibitors, tobacco smoking, higher systolic blood pressure, higher uACR, and coinheritance of high‐risk APOL1 status while a higher hemoglobin concentration was associated with a less rapid annual eGFR decline (Table 2).