Fluorescence observations indicated that MARCH2 overexpression reduced ALV-A-GFP replication (Fig. 1F), and a flow cytometric analysis revealed a 10% decrease in the ALV-A-GFP infection rate in DF-1-MARCH2 cells compared to that in wild-type (WT) cells (Fig. 1G). The gene discussed is MARCHF2; the disease is infection.