FMR1 and Alzheimer disease: We initially investigated whether genetic reduction of FMRP or 4E‐BP2 prevented the attenuation of hippocampal protein synthesis induced by amyloid‐β oligomers (AβOs), soluble neurotoxins that accumulate in AD brains and cause synapse failure and cognitive impairment (Ferreira et al. 2015; Lourenco et al. 2013).