Recent work also identified Nestin as a critical regulator of autophagy-dependent ferroptosis in muscle atrophy; Nestin interacts with MAP1LC3B (LC3B), catalyzing its polyubiquitination to inhibit autophagy flux and suppress ferroptosis, whereas Nestin knockout exacerbates atrophy (Morgan et al., 2018b). Here, MAP1LC3B is linked to Atrophy.