PDGFs and their corresponding receptors, PDGFRα and PDGFRβ, exhibit expression in a diverse range of malignant tumors, such as non-small cell lung cancer (NSCLC), gastrointestinal stromal tumor (GIST), pancreatic cancer, breast cancer, ovarian carcinoma and hepatocellular carcinoma (Pandey et al., 2023). This evidence concerns the gene PDGFRB and familial pancreatic carcinoma.