TP53 and neoplasm: M27-39@FA-MCNs induced tumor cell apoptosis and restrained tumor growth by targeting the mitochondria of tumor cells, interfering with mitochondrial energy metabolic processes, activating the P53/caspase-3 mitochondrial apoptosis pathway, and reducing the standard of proinflammatory cytokines IL-6, IL-17, interferon-γ (IFN-γ), and IL-1β.