This was accomplished through the suppression of NLR family CARD domain containing 4 (NLRC4) inflammasome activation and a decrease in the expression of matrix metalloproteinase-9 (MMP-9) in both house dust mite-exposed mice and stimulated human bronchial epithelial cell lines, suggesting its promise as a management option for asthma (36). The gene discussed is MMP9; the disease is asthma.