Compared with co-cultures containing GFP-DCs, the average concentrations of IFN-γ and granzyme B in neoantigen-reactive T cells from patients CRC-1 and CRC-2, co-cultured with 12GM-DCs, were significantly higher (Figures 5D, E); the expression levels of CD62L and CD45RO also were significantly upregulated (Figure 5F). Here, IFNG is linked to colorectal carcinoma.