CACNA1C and Timothy syndrome: Through efforts by KWT, the Timothy Syndrome Foundation (TSF) and the Timothy Syndrome Alliance (TSA) to raise awareness, the number of identified living individuals with CACNA1C-Related Disorders has risen in the past five years alone from ~ 40 to > 200, with rapid growth coinciding with the inclusion of CACNA1C in a range of gene-screening panels and clinical implementation of comprehensive non-targeted next-generation (exome or genome) sequencing.