Exonic deletions in NRXN1, particularly those affecting the NRXN1α isoform, have been found to confer substantially elevated risk for schizophrenia, with odds ratios (OR) ranging from 7.44 to 14.4 in large multi-cohort studies (Rujescu et al., 2009; Ikeda et al., 2010; Hu et al., 2019). Here, NRXN1 is linked to schizophrenia.