ADAMTS13 and thrombotic thrombocytopenic purpura: Diagnosis is based on the triad of AKI, microangiopathic anemia and thrombocytopenia, but requires exclusion of other TMAs—such as typical HUS and thrombotic thrombocytopenic purpura (TTP)—via stool cultures and ADAMTS13 activity testing (Goodship et al., 2017; Brocklebank et al., 2023; Brocklebank et al., 2018).