Using the “irGSEA” package, we scored hallmark pathways: Macro_1_FCGR3A showed downregulation of IL6-JAK-STAT3 but upregulation of PI3K-AKT-mTOR and TNF-NFκB signaling (Fig. 6B), suggesting an anti‐sepsis role. The gene discussed is AKT1; the disease is Sepsis.