While the accumulation of macrophages in diabetic kidneys was accompanied with an increased expression of proinflammatory genes (Tnf, Ccl2, Nos2, Nlrp3 – Table 1) associated with classical M1 macrophage activation, this was not affected by myeloid MR deficiency and was not seen in the diabetic hearts (Table 2). This evidence concerns the gene NR3C2 and hyperinsulinemic hypoglycemia, familial, 4.