For instance, lncRNA–miRNA axes such as MEG3/miR-664a and TUG1/miR-144-3p have been mechanistically linked to OS progression [38, 39]; knockdown of the oncogene lncRNA NEAT1 restores the availability of miR-34c and delays the tumor growth in osteosarcoma [40]. The gene discussed is TUG1; the disease is neoplasm.