Regarding specific AEs, significant differences were observed for diarrhea of any grade across the three groups (AB: 66.0%, RB: 3.4%, PB: 8.9%, p < 0.001), for neutropenia of any grade (AB: 40.4%, RB: 79.7%, PB: 80.4%, p < 0.001), thrombocytopenia of any grade (AB: 29.8%, RB: 13.6%, PB: 32.1%, p = 0.04) and increasing AST/ALT of any grade (AB: 36.2%, RB: 25.4%, PB: 10.7%, p = 0.008) as well as grade 3–4 neutropenia (AB: 25.5%, RB: 35.6%, PB: 62.5%, p < 0.001), grade 3–4 anemia (AB: 8.5%, RB: 0%, PB: 0%, p < 0.001), and grade 3–4 diarrea (AB: 10.6%, RB: 3.4%, PB: 0%, p = 0.03). This evidence concerns the gene GPT and Decreased total neutrophil count.