TMEM175 and Parkinson disease: The known risk factor in TMEM175, p. Met393Thr was found to be significantly associated with PD in the GP2-SAS cohort [corrected P value = 0.010, OR (95%CI) = 1.83(1.28–2.61)], and GP2-AJ cohort [corrected P value = 0.023, OR (95%CI) = 1.43 (1.13–1.80)].