RYR2 and Arrhythmogenic right ventricular dysplasia: The diagnostic yield of ARVC was 89%, with causative mutations in 15/17 probands (4 with DSP, 4 with PKP2, 4 with DSG2, 1 with RYR2, 1 with TMEM43, 1 with CACNa1AC, and 2 were negative).