Macrophages in the myopia group upregulated proinflammatory Ifitm3/6, Apoc1, and Bst2-Siglech in the large intestine, proinflammatory ly6c1, Apoc1, and S100a in the liver, and ly6c1 and S100a in the kidney (Fig. 4c). This evidence concerns the gene IFITM3 and myopia.