FOXA1 and Familial prostate cancer: Results showed that FOXA1 expression was significantly higher in prostate cancer cell lines such as LNCaP, PC-3, and DU145 compared to the normal prostate cell line RWPE-1, and SLC7A11 expression was positively correlated with FOXA1 expression, being notably upregulated in prostate cancer cell lines (Supplementary Fig. 1 F-H).