There were eight protective genes (DHODH,DHRS7B,TOP1MT,CASP8,GFM1,CPT1B,TK2,GPD2), and four genes (SCP2,DMPK,GSTK1,SIRT3) that increased delirium risk, as shown inFigure 2, withp = 0.05 (dotted line); and false discovery rate (FDR) < 0.05 (red asterisks). Here, SIRT3 is linked to delirium.