Compared to the control group that drank regular water, neither Tbr1+/− nor WT mice administered the 1/4 cocktail exhibited a difference in behavior in the open field or elevated plus maze assays (Fig 8C and 8D), consistent with our previous observation that Tbr1 haploinsufficiency does not influence locomotion or anxiety [39]. The gene discussed is TBR1; the disease is Anxiety.