In contrast, genetic depletion of BECN1, ATG5, p62/SQSTM1, or LAMP1 or pharmacological inhibition by chloroquine, resensitizes breast cancer cells to PARPi by shifting DNA repair towards error‐prone NHEJ (non‐homologous end joining), leading to mitotic catastrophe and genomic instability [116]. The gene discussed is SQSTM1; the disease is breast carcinoma.