S100B and neurosarcoidosis: In a review other biomarkers in neurosarcoidosis such as CSF sIL-2R, IL-6, CD4/CD8 ratio, neopterin, CCL2, S100B, absence of MRZ reaction, KL-6, serum IL-10, Amyloid A1 and plasma S100B are described as candidate biomarkers, but many lack specificity and their value in distinguishing neurosarcoidosis from other infectious or inflammatory diseases is yet unclear.42