Aimed at evaluating the antihypertensive effect of the natural polyphenol catechin (CAT) and its action on renal arachidonic acid (AA) metabolism in comparison to captopril (CAP), this study demonstrated that both low and high doses of CAT attenuated the development of hypertension in SHRs. Notably, the high‐dose group exhibited a significant blood pressure reduction relative to the untreated controls. Here, CAT is linked to Hypertension.