Women aged below (N = 65) and above (N = 109) 40 did not significantly differ in baseline prolactin levels, BMI, C-reactive protein, smoking habits, rates of hyperprolactinaemia, proportion of affective versus non-affective diagnosis, proportion of prolactin-raising antipsychotics, dose equivalents of antipsychotics and proportion of antipsychotics metabolised by CYP 1A2 (as opposed for 3A4 – for those on antipsychotic monotherapy only) (Table 1). The gene discussed is PRL; the disease is hyperpituitarism.