After treatment of LPS (2 μg/ml, 24 h) mimicking infection, the Vmax of action potentials at 1 and 2 Hz was reduced in BrS1 (Fig. 5a-d), and the APD50 of action potentials at 1 and 2 Hz was shortened in BrS2 (Fig. 5a-d). This evidence concerns the gene GRPR and infection.