MACROH2A1 and Alzheimer disease: The level of macroH2A1 mRNA expression in male mouse cortex was subject to a Genotype × Treatment interaction [F(1, 20) = 4.69, p = 0.04], whereby GDX reduced macroH2A1 levels in AD but not WT male mice [Fig. 5, q = 0.02 for AD Sham vs. GDX), q = 0.29 for WT Sham vs. GDX].