This interaction was closely reflected in the findings of this study, as it was predicted that another miRNA, miR-6754-5p, was sponged by circVCAN to up-regulate the expression of MEF2D. Moreover, Yao, Li (2012) [121] proposed the use of bis(3)-cognition to activate MEF2D, which they achieved to ameliorate motor defects by maintaining redox homeostasis and restoring tyrosine hydroxylase signal in the substantia nigra of PD samples. Here, MEF2D is linked to Parkinson disease.