TGFB1 and posterior cortical atrophy: Likewise, the HALLMARK_TGFbeta_signaling pathway was strongly represented in C3 cultures and LAPC9 stroma with TGFβ target genes abundantly expressed in the NEPC and mCRPC-enriched myCAF clusters of the PCA, PCCAT and PCa GEMM single cell atlases (Supplemental Fig. S7-9, S13).