For example, in AD, AS events such as exon 8 exclusion in Amyloid‐beta (Aβ) Precursor Protein‐binding Family B, Member 2 (APBB2), can affect Aβ production, a key component of abnormal protein deposits in the brain; similarly, exon 10 inclusion/exclusion in Microtubule‐Associated Protein Tau (MAPT) can alter tau isoform ratios, contributing to neurofibrillary tangle formation, which disrupts neural communication and leads to neuron loss (Love et al. 2015). This evidence concerns the gene MAPT and Alzheimer disease.