Unlike other epilepsy models in which apneas cluster ictally or postictally (Marincovich et al., 2021; Bacq et al., 2022; Wenker et al., 2022), PTEN–cKO mice exhibit a progressive rise in brief interictal apneas, but rare peri-ictal apneas prior to PEA. This evidence concerns the gene PTEN and epilepsy.