Given ITPR1's well‐established role in autosomal dominant SCA15, along with previously described cases with cerebellar ataxia and peripheral neuropathy and supporting evidence from our clinical experience with other genes—such as PNPT1‐related ataxia and CANVAS causing SAN—we consider a deletion of ITPR1 to be a plausible explanation for the patient's neurological phenotype. This evidence concerns the gene ITPR1 and aceruloplasminemia.