PHGDH and sarcopenia: In the Sarcopenia dataset GSE8479, the difference results showed that FOXO1, CTH, HSD11B1, PKM, PHGDH, GSTK1, SPTSSA, and PRDM2 expression were highly statistically different (p-value < 0.001) between the Sarcopenia group and the Control group (Fig 5B).