Furthermore, we found significant positive correlations with estimated zinc deficiency prevalence (p-value < 0.05) for five of the eleven GWAS SNPs, including variants in SLC39A4, SLC30A8, SLC30A2, DPEP1, and RB1/RCBTB2 (Fig 5A and Table F in S1 File), supporting an overall trend that zinc-increasing alleles correlate with estimated zinc deficiency (one-sided binomial test p-value = 1.12E-04). The gene discussed is SLC30A8; the disease is Zinc deficiency.